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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: BRWD1 All Species: 16.97
Human Site: S822 Identified Species: 37.33
UniProt: Q9NSI6 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0.2
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NSI6 NP_061836.2 2320 262920 S822 L S S G N E S S S S V R H E T
Chimpanzee Pan troglodytes XP_001170924 2320 262999 S822 L S S G N E S S S S V R H E T
Rhesus Macaque Macaca mulatta XP_001108655 2320 262912 S822 L S S G N E S S S S V R H E T
Dog Lupus familis XP_544889 2401 270094 S896 E L S S G N E S S S S I R H T
Cat Felis silvestris
Mouse Mus musculus Q921C3 2304 259007 S823 L S S G N E S S G S V R H E T
Rat Rattus norvegicus XP_001054667 1799 202807 F370 D K V V A V Q F C N N G D S L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510724 2599 293992 D821 E S S C E E E D E S V M D E M
Chicken Gallus gallus XP_416730 2299 260504 S820 N N I E Q L D S S D E E R D D
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_001920441 2191 247687 G756 I P E L T P S G Y R A Q E S F
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_395863 1676 190205 D247 L L A A G S L D R I L R V W C
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001201169 1837 210307 T408 V Y E L Y G H T D E V Y V L E
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.4 97.9 85.7 N.A. 78.7 44.7 N.A. 65.6 61.8 N.A. 44.7 N.A. N.A. 34.9 N.A. 27.3
Protein Similarity: 100 99.7 98.7 89.7 N.A. 86.1 57.7 N.A. 74.3 73.4 N.A. 61.4 N.A. N.A. 49.4 N.A. 42.3
P-Site Identity: 100 100 100 33.3 N.A. 93.3 0 N.A. 40 13.3 N.A. 6.6 N.A. N.A. 13.3 N.A. 6.6
P-Site Similarity: 100 100 100 33.3 N.A. 93.3 6.6 N.A. 40 26.6 N.A. 20 N.A. N.A. 26.6 N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 10 10 10 0 0 0 0 0 10 0 0 0 0 % A
% Cys: 0 0 0 10 0 0 0 0 10 0 0 0 0 0 10 % C
% Asp: 10 0 0 0 0 0 10 19 10 10 0 0 19 10 10 % D
% Glu: 19 0 19 10 10 46 19 0 10 10 10 10 10 46 10 % E
% Phe: 0 0 0 0 0 0 0 10 0 0 0 0 0 0 10 % F
% Gly: 0 0 0 37 19 10 0 10 10 0 0 10 0 0 0 % G
% His: 0 0 0 0 0 0 10 0 0 0 0 0 37 10 0 % H
% Ile: 10 0 10 0 0 0 0 0 0 10 0 10 0 0 0 % I
% Lys: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 46 19 0 19 0 10 10 0 0 0 10 0 0 10 10 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 10 % M
% Asn: 10 10 0 0 37 10 0 0 0 10 10 0 0 0 0 % N
% Pro: 0 10 0 0 0 10 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 10 0 10 0 0 0 0 10 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 10 10 0 46 19 0 0 % R
% Ser: 0 46 55 10 0 10 46 55 46 55 10 0 0 19 0 % S
% Thr: 0 0 0 0 10 0 0 10 0 0 0 0 0 0 46 % T
% Val: 10 0 10 10 0 10 0 0 0 0 55 0 19 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % W
% Tyr: 0 10 0 0 10 0 0 0 10 0 0 10 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _